Paracetamol standard 21.2mg placed in 100ml volumetric flask was added water to dissolve and dilute to the scale.Then take 20ul injected into HPLC,peak area record was 8,012,590.While take paracetamol tablet powders 0.1459g placed in 100ml flask,adde
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Paracetamol standard 21.2mg placed in 100ml volumetric flask was added water to dissolve and dilute to the scale.Then take 20ul injected into HPLC,peak area record was 8,012,590.While take paracetamol tablet powders 0.1459g placed in 100ml flask,added water to dissolve and dilute to scale,filter.Take 20ul filtrate injected into HPLC,the peak area record was 7,960,076,the tablet labeled amounts of paracetamol was 20mg / film,content limits were 90% 110% of the labeled amount.Please calculated the theoretical tablet weight range.
扑热息痛 对照:21.2mg 到 100ml 20ul峰面积8012590
样品粉:0.1459g 到 100ml 20ul峰面积7960076
理论含量:20mg/片 90%~110%
8012590/21.2*100=7960076/(0.1459/理论片重*20)*100
理论片重=0.1385g
片重范围:0.1247~0.1524
Paracetamol standard 21.2mg placed in 100ml volumetric flask was added water to dissolve and dilute to the scale.Then take 20ul injected into HPLC,peak area record was 8,012,590.While take paracetamol tablet powders 0.1459g placed in 100ml flask,adde
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