学帮网英语翻译PET18F-FDG-PET/CT is now generally regarded as the most effectiveimaging tool for the whole-body evaluation of NSCLC(Fig.1),and recent studies suggest it is equally effective insmall cell carcinoma.18 As it detects the presence of tumor b
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英语翻译
PET
18F-FDG-PET/CT is now generally regarded as the most effective
imaging tool for the whole-body evaluation of NSCLC
(Fig.1),and recent studies suggest it is equally effective in
small cell carcinoma.18 As it detects the presence of tumor by
increased cellular metabolic activity,rather than,like scintigraphy,
indirectly through increased osteoblastic activity,it
may enable earlier detection of metastatic foci.19 In a direct
comparative study,accuracy of PET and scintigraphy in the
detection of bony metastases in newly diagnosed lung cancer
were 94% and 85%,respectively,with sensitivity values of
91% and 75%,and specificity of 96% and 95%,respectively.
20 This suggests that 18F-FDG-PET could replace the staging
role of bone scintigraphy.The vast majority of bony metastases
from all types of lung carcinomas show a lytic pattern,
usually making them readily detectable on both the CT and PET
components of the study.It has been noted that CT-positive but
PET-negative lesions are significantly more prevalent posttherapy.
5 These may appear osteoblastic,
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