that引导的主语从句That almost current reports which lack systemic analysis are presented as case reports leads to incompleteunderstanding of risk factors,clinical symptoms,radiologic features,treatmentof skeletal cryptococcosis.

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that引导的主语从句
That almost current reports which lack systemic analysis are presented as case reports leads to incompleteunderstanding of risk factors,clinical symptoms,radiologic features,treatmentof skeletal cryptococcosis.

这个用法没有问题.
(主语从句 )That + 陈述句 可以放在句首.
这句话的结构是That + almost current reports which (定语从句) lack systemic analysis(定语从句到此结束) are...
所以简写一下就是 Current reports are presented as case reports...