(a+2)(a-2)(a²*²+4a²+16)

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(a+2)(a-2)(a²*²+4a²+16)

(a+2)(a-2)(a^4+4a²+16)
=(a²-4)*(a²+4)²
=(a²-4)*(a²+4)*(a²+4)
=(a^4-16)*(a²+4)
=a^6+4a^4-16a²-64