Who can help me?Thanks我想请问Sure 和Of cause 在用法上有什么区别?另外,那at 和in 的用法又有什么分别呢?

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Who can help me?Thanks
我想请问Sure 和Of cause 在用法上有什么区别?另外,那at 和in 的用法又有什么分别呢?

sure:行.只指当时的那一次,
of cause:行.表达一种责任,
at和in在用法有许多的用途.
指时间:at指具体的时间点,而in则指一个时间段.
指地点:at指小地点,in则指大地点.

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